JOURNAL PUBLICATIONS

• G. Han, K. Khosla, K. T. Smith, D. W. H. Ng, JiYong Lee, X. Ouyang, J. C. Bischof, and M. C. McAlpine*, 3D Printed Organisms Enabled by Aspiration-Assisted Adaptive Strategies, Advanced Science, 2404617 (2024), https://doi.org/10.1002/advs.202404617.

• J. Kim, H. Kim, S.H Park, S. Y. Han, H. Hong, Y. J. Kim, JiYong Lee, J. Kim, S.-W. Cho, W.H. Ryu. Individually-addressable composite microneedle electrode array by mold-and-place method for glucose detection, Sensors and Actuators B: Chemical, Vol. 401, 134884 (2024), https://doi.org/10.1016/j.snb.2023.134884.

• Y. Kang†, JiYong Lee†, S.H. Park, J. H. Kim, S. I. Kim, and W.H. Ryu*, Balloon Catheter-integrated Piezoelectric Micro-pyramid Arrays for Measuring Vascular Stiffness, ACS Applied Materials & Interfaces, Vol.15, No.14, 17653–17663 (2023), https://doi.org/10.1021/acsami.3c00700, †Equally contributed.

• E.H. Jang, J. Ryu, J.-H. Kim, JiYong Lee, W.H. Ryu, and Y.-N. Youn*. Effect of sequential release of sirolimus and rosuvastatin using silk fibroin microneedle to prevent intimal hyperplasia, Biomedicine & Pharmacotherapy, Vol. 168, 115702 (2023), https://doi.org/10.1016/j.biopha.2023.115702.

• C. Liu†, J.-T. Kim†, D. S. Yang†, D. Cho†, S. Yoo, S. R. Madhvapathy, H. Jeong, T. Yang, H. Luan, R. Avila, J. Park, Y. Wu, K. Bryant, M. Cho, JiYong Lee, J. Kwak, W. Ryu, Y. Huang*, R. G. Nuzzo*, and J. A. Rogers*, Multifunctional Materials Strategies for Enhanced Safety of Wireless, Skin-Interfaced Bioelectronic Devices, Advanced Functional Materials, 2302256 (2023), https://doi.org/10.1002/adfm.202302256, †Equally contributed.

• J.-H. Kim, E. H. Jang, J.-Y. Ryu, JiYong Lee, J. H. Kim, W. Ryu, Y.-N. Youn* Sirolimus-Embedded Silk Microneedle Wrap to Prevent Neointimal Hyperplasia in Vein Graft Model, International Journal of Molecular Science, Vol 24. No.4, 3306 (2023), https://doi.org/10.3390/ijms24043306.

• Y. Kim, JiYong Lee, H. Hong, S. Park, and W.H. Ryu*, Self-powered Wearable Micropyramid Piezoelectric Film Sensor for Real Time Monitoring of Blood Pressure, Advanced Engineering Materials, Vol.25 No.2 2200873 (2022), https://doi.org/10.1002/adem.202200873.

• Y. Xue, H. Kim, J. Lee, Y. Liu, T. Hoffman, Y. Chen, X. Wu, W. Sun, S. Zhang, H. Cho, JiYong Lee, H. Kang, W. Ryu, C. Lee, S. Ahadian, M.R. Dokmeci, B. Lei, K. Lee*, A. Khademhosseini*, Co-electrospun Silk Fibroin and Gelatin Methacryloyl Sheet Seeded with Mesenchymal Stem Cells for Tendon Regeneration, Small, 2107714, Vol. 10. No. 21, 2107714 (2022), https://doi.org/10.1002/smll.202107714.

• E. H. Jang, J.-H. Kim, J. Ryu, JiYong Lee, H.-H Kim and Y.-N. Youn*, Time-dependent pathobiological and physiological changes of implanted vein grafts in a canine model, Journal of Cardiovascular Translational Research, 1-11 (2022), https://doi.org/10.1007/s12265-022-10226-z.

• JiYong Lee, E. H. Jang, J. H. Kim, S.H. Park, Y. Kang, S. Park, K.J. Lee, J.-H. Kim, Y.-N. Youn*, and W.H. Ryu*, Highly Flexible and Porous Silk Fibroin Microneedle Wraps for Perivascular Drug Delivery, Journal of Controlled Release, Vol.340, 125-135 (2021) Selected as the Outside Front Cover of 2021. Vol. 340, https://doi.org/10.1016/j.jconrel.2021.10.024.

• S.H. Park, Y. J. Kim, S. Park, H. Hong, JiYong Lee, S. I. Kim, K. Lee, and W.H. Ryu*, Rapid Extraction and Detection of Biomolecules via a Microneedle Array of Wet-crosslinked Methacrylated Hyaluronic Acid, Advanced Materials Technologies, 2100874 (2021), https://doi.org/10.1002/admt.202100874.

• S.H. Park, K.J. Lee, H. Kang, Y. Lee, JiYong Lee, J. H. Kim, H. B. Song*, and W.H. Ryu*, Single administration of a biodegradable, separable microneedle can substitute for repeated application of eyedrops in the treatment of infectious keratitis, Advanced Healthcare Materials, Vol.10, No.11, 2002287 (2021), https://doi.org/10.1002/adhm.202002287.

• K.J. Lee, JiYong Lee, S. G. Lee, S.H. Park, D.S. Yang, J.-J. Lee, A. Khademhosseini, J. S. Kim, and W.H. Ryu*, Microneedle drug eluting balloon for enhanced drug delivery to vascular tissue, Journal of Controlled Release, Vol.321, 174-183 (2020), https://doi.org/10.1016/j.jconrel.2020.02.012.

• K.J. Lee, S.H. Park, JiYong Lee, S. Ryu, C.Joo, and W.H. Ryu*, Three-Step Thermal Drawing for Rapid Prototyping of Highly Customizable Microneedles for Vascular Tissue Insertion, Pharmaceutics, Vol.11, No.3, 100-112 (2019), https://doi.org/10.3390/pharmaceutics11030100.

• S. K. Jeon, JiYong Lee, H. S. Hwang, W.H. Ryu* and Y. Chae*, A parasitic insensitive catheter-based capacitive force sensor for cardiovascular diagnosis, IEEE Transactions on Biomedical Circuits. and Systems, Vol.12, No.4, 7614-7625 (2018), https://doi.org/10.1109/TBCAS.2018.2832172.

• JiYong Lee, D.-H. Kim, K. J. Lee, I. H. Seo, S. H. Park, E. H. Jang, Y. Park, Y.-N. Youn*, and W.H. Ryu*, Transfer-molded wrappable microneedle meshes for perivascular drug delivery, Journal of Controlled Release, Vol.268, 237-246 (2017), https://doi.org/10.1016/j.jconrel.2017.10.007.

• D.-H. Kim, E. H. Jang, K. J. Lee, JiYong Lee, S. H. Park, I. H. Seo, K. W. Lee, S. H. Lee, W.H. Ryu*, and Y.-N. Youn*, A Biodegradable Microneedle Cuff for Comparison of Drug Effects through Perivascular Delivery to Balloon-Injured Arteries, Polymers, Vol.9, No.2, 56-68 (2017), https://doi.org/10.3390/polym9020056.

• E. Ko, J. S. Lee, H. Kim, S. Y. Yang, D. Yang, K. Yang, JiYong Lee, J. Shin, H. S. Yang, W.H. Ryu*, and S.-W. Cho*, Electrospun Silk Fibroin Nanofibrous Scaffolds with Two-Stage Hydroxyapatite Functionalization for Enhancing the Osteogenic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells, ACS applied materials & interfaces, Vol.10, No.9, 7614-7625 (2017), https://doi.org/10.1021/acsami.7b03328.

• H.B. Sim, JiYong Lee, B. Park, S. J. Kim, S. Kang, W.H. Ryu*, and S. C. Jun*, High-concentration dispersions of exfoliated MoS2 sheets stabilized by freeze-dried silk fibroin powder, Nano Research, Vol.9, No.6, 1709-1722 (2016), https://doi.org/10.1007/s12274-016-1065-2.

• S. H. Park, K. J. Lee, JiYong Lee, J. H. Yoon, D. H. Jo, J. H. Kim, K. Kang, and W.H. Ryu*, Microneedle-based minimally-invasive measurement of puncture resistance and fracture toughness of sclera, Acta Biomaterialia, Vol.44, No.15, 286-294 (2016), https://doi.org/10.1016/j.actbio.2016.08.011.

• D. Yang, H. Kim, JiYong Lee, H. Jeon, and W.H. Ryu*, Direct modulus measurement of single composite nanofibers of silk fibroin/hydroxyapatite nanoparticles, Composites Science and Technology, Vol.122, No.18, 113-121 (2016), https://doi.org/10.1016/j.compscitech.2015.11.019.

• JiYong Lee, S. H. Park, I. H. Seo, K. J. Lee, and W.H. Ryu*, Rapid and repeatable fabrication of high A/R silk fibroin microneedles using thermally-drawn micromolds, European Journal of Pharmaceutics and Biopharmaceutics, Vol.94, 11-19 (2015), https://doi.org/10.1016/j.ejpb.2015.04.024.

• H. B. Song, K. J. Lee, I. H. Seo, JiYong Lee, S.-M. Lee, J. H. Kim, J. H. Kim*, and W.H. Ryu*, Impact insertion of transfer-molded microneedle for localized and minimally invasive ocular drug delivery, Journal of Controlled Release, Vol.209, 272-279 (2015), https://doi.org/10.1016/j.jconrel.2015.04.041.

• K. J. Lee, S. H. Park, JiYong Lee, H. C. Joo, E. H. Jang, Y.-N. Youn*, and W.H. Ryu*, Perivascular biodegradable microneedle cuff for reduction of neointima formation after vascular injury, Journal of Controlled Release, Vol.192, 174-181 (2014), https://doi.org/10.1016/j.jconrel.2014.07.007.

BOOK CHAPTERS

• K. J. Lee, S. H. Park, JiYong Lee, and W.H. Ryu*, Commercialized Microneedles (Ch. 9, pp 91- 108) in "Microneedling in Clinical Practice" (CRC Press, 2020.10.02) Ed. by. B. Stoeber, R. K. Sivamani, H. I. Maibach, eBook ISBN (9781315265612), https://doi.org/10.1201/9781315265612. 

PATENTS

• W.H. Ryu, JiYong Lee, S.H. Park and J.H. Kim, “MICRONEEDLE PATCH, MICRONEEDLE SYSTEM, AND METHOD OF FABRICATING THE SAME”, US Patent, 11697009 (2023).

• W.H. Ryu, JiYong Lee, J.M. Kim, “BIOLOGICAL DATA ACQUISITION APPARATUS AND BIOLOGICAL DATA PROCESSING APPARATUS USING THE SAME”, Korea Patent, 10-2742895 (2024).

• W.H. Ryu, Y.-N. Youn, JiYong Lee, E. H. Jang, and J. H. Kim, “DRUG DELIVERY STENT, METHOD OF FABRICATING THEREOF AND METHOD OF DELIVERING DRUG USING THE SAME”, Korea Patent, 10-2428943 (2022).

• W.H. Ryu, Y-N. Youn, JiYong Lee, E. H. Jang, and J. H. Kim, “DRUG DELIVERY DEVICE AND METHOD OF DRUG DELIVERING USING THE SAME”, Korea Patent, 10-2428946 (2022).

• W.H. Ryu, JiYong Lee, S.H. Park and J.H. Kim, “MICRO-NEEDLE PATCH AND METHOD OF FABRICATING THE SAME”, Korea Patent, 10-2297112 (2021).

• W.H. Ryu, JiYong Lee, S.H. Park and J.H. Kim, “MICRO-NEEDLE PATCH AND MICRO-NEEDLE SYSTEM”, Korea Patent, 10-2323528 (2021).

• W.H. Ryu, JiYong Lee, and Y.-N. Youn, “MESH FOR MEDICAL HAVING MICRO NEEDLES AND MANUFACTURING METHOD THEREOF”, Korea Patent, 10-1850957 (2018).

• S. C. Jun, H. B. Sim, W.H. Ryu, S. Kim, Y. S. H. Han, and JiYong Lee, “EXFOLIATIONG METHOD OF SEMICONDUCTING MATERIAL FOR PREPARING 2D MATERIAL USING SILK”, Korea Patent, 10-1633631 (2016).

• W.H. Ryu, JiYong Lee, J.M. Kim, “BIOLOGICAL DATA ACQUISITION APPARATUS AND BIOLOGICAL DATA PROCESSING APPARATUS USING THE SAME”, US Patent, 17/520,130 (pending).

• W.H. Ryu, Y.-N. Youn, JiYong Lee, E. H. Jang, and J. H. Kim, “DRUG DELIVERY STENT, METHOD OF FABRICATING THEREOF AND METHOD OF DELIVERING DRUG USING THE SAME”, International Patent, PCT/KR2021/013794 (pending),

• W.H. Ryu, JiYong Lee, and J. Kim, “MEDICAL BALLOON CATHETER SENSOR MICRONEEDLE FORMED THEREIN”, Korea Patent, 10-2020-0148092 (pending).

• W.H. Ryu, JiYong Lee, S.H. Park and J.H. Kim, “MICRONEEDLE PATCH AND METHOD OF FABRICATING THE SAME”, Korea Patent, 10-2019-0110987 (pending).